Recommended dosage (adults): SAMe should always be taken on an empty stomach. SAMe must be taken for a minimum of 2 weeks, at which time effects should be observed.
For mood balance: 1–4 tablets, 2 times daily, or as directed by a physician. Consult a physician for use beyond 6 weeks.
For osteoarthritic pain: 1–3 tablets, 2 times daily, not to exceed 6 tablets per day, or as directed by a physician. Consult a physician for use beyond 12 weeks.

Caution

Always read the label for full list of cautions and warnings. Please consult a health care practitioner before use. Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature out of direct sunlight.